Everyone is talking about Web 2.0 – but only slowly the benefits of it are being integrated into consumer products. Here we introduce two novel examples for technologies greatly improving everyday products by adding features only possible thanks to the web.
The first product is Lytro, a camera capturing pictures without the need of focusing. The camera does not even look like a camera any more; it is just an angular aluminum tube surrounding the lens, with the aperture at one end and a display screen at the other – no viewer, no control buttons, only a power button, a shutter button and a zoom slider.
Just point and shoot, and focusing is done once the picture has been uploaded to the web. Simply push the mouse over the area of interest, click, and the focus is there. The pictures are HD quality, and users can switch between 2D and 3D views.
Technically, Lytro captures the entire light field of the scene when the shutter button is pressed, i.e. a sensor records not only color and intensity of the light rays, but also the vector direction – an information that is completely lost with conventional cameras. This information is later used to enable the selection of different batches of light, i.e. bringing different parts of the picture into focus.
The second product is Libroid, an ebook format designed to present books electronically not just by bringing letters to a screen, but by adding extra information such as films, photos, maps, links in a way that readers are not distracted if they choose to focus on the text.
The application designed for iPads is simple. Hold your iPad in portrait format and you can read the text without distraction by additional elements. If you switch to landscape format, two columns appear on the left and right side of the text. As an example, one column may display photos, while the other refers to further reading, etc. The columns scroll with the text so that always only matching information is displayed.
This is much more than just adding an interview with the author or some photos to an ebook. It allows for entirely new writing: a thriller author might provide the same scene from the perspective of different characters so that readers can switch easily between their heroes, a cookbook author may add videos or provide features to simply adapt recipe quantities to the number of eaters or recipe variations; non-fiction authors may provide sources, their research material and much more.
Both products already are on the market. Lytro sell its cameras from $399 in the US, while Libroid is available in Apple’s iTunes store (iPad only) for €7,99. Juergen Neffe, inventor of Libroid, still appreciates investors as German publishing houses keep being very conservative and are still not embracing the ebook market wholeheartedly.
The human genome of newborns contains an unexpectedly low number of mutations, writes Joachim Müller-Jung in Frankfurter Allgemeine Zeitung (FAZ). Contrary to earlier estimates of 100-200 mutations generated in the germ cells of parents, the number is only about 60. Results come from sequencing the entire genomes of two families with one child each. The results have implications for understanding human evolution and genetics.
Sonja Kastilian, also in FAZ, features a preliminary report of IQWiG, Germany’s watchdog agency appraising drugs and treatments for quality and cost effectiveness, on the benefits of HPV testing of women as a screening for ovarian cancer. IQWiG set out to compare DNA tests for HPV with common pap smear tests and reported that the HPV tests leas to an earlier diagnosis and better follow-up examinations, regardlesss of whether it is applied alone or in combination with the conventional test. A final decision on whether the test is to be reimbursed by Germany’s statutory healthcare system is expected for 2012. In 2006, the Joint Federal Committee (G-BA), the body in charge, had voted against reimbursement for cost reasons. Kastilian also points out that HPV vaccination rates at present are below 30% in young women in Germany, in contrast to up to 81% in the UK, Portugal, and Australia. Reason has been an unduly discussion in German media about potential risks, high costs and lack of efficacy.
Uta Neubauer in Neue Zürcher Zeitung (NZZ) reports on novel approaches to use cold plasma to disinfect wounds, hands, and food. A method and device developed by the German Max Planck Institute for Extraterrestrial Physics has already demonstrated safety and efficacy in treating wounds and disinfecting hands. At present, it is under investigation for the treatment of foods, e.g. food additives and berries.
Sven Titz, also in NZZ, deals with latest insights into the physics of the water surface. Using vibration spectroscopy, physicists of the University of Southern California at Los Angeles found that the surface is made up basically by -OH groups of the water molecules sticking out from the liquid. The discovery will lead to better understanding solubility of molecules in water.
Forbes this week introduces two innovations in optics. Jennifer Hicks writes about the “socialization of the microscope” by a technology that allows the display of microscopic images on an extremely large multitouch screen, just like an oversized iPad. Thereby, groups of students, pathologists or researchers can focus on tiny details by touching, gesturing, and zooming in and out. A video of the microscope at work can be found here.
Californian-based start-up Lytro has unveiled a camera that can take pictures without focusing, writes Tomio Geron in Forbes. Instead, focusing on any point of interest in the photo is done once the image is loaded on a computer. The consumer camera is based on the light field technology invented by Stanford University researchers. The camera is fitted with special lenses and a sensor that captures every ray of light hitting it, regardless of whether it is from the fore- or the background, and records its individual color, intensity and direction. The camera therefore also can be used to generate 3D-pictures. Examples can be found here.
The Economist this week introduces an intelligent drug delivery approach using nanoparticles. It can be used to deliver anti-cancer chemotherapeutic drugs and makes use of the blood-clotting mechanism: first, nano-sized golden rods are injected into the blood stream. They fit into the unusual pores common in capillaries nourishing tumors and thereby mark tumor sites. Once they are in place, the tumor site is treated with laser light bursts. Their energy is absorbed by the gold and converted to heat destroying the capillaries so that the body’s coagulation system is triggered to repair the damage. This is when the second nanoparticles come into play. They carry the chemotherapeutics together with a fibrin-binding protein fragment and are designed to release the drug upon fibrin-binding only. The treatment strategy therefore delivers the drug exactly to the site the coagulation system is active, that is, at the tumor. The method developed at the Massachusetts Institute of Technology (MIT) has proven safety and efficacy in mice and will be tested in humans soon.
Researchers from the University of Rochester have come up with just another idea to release drugs on target, the New Scientistreports. They found that nanocarbon tubes containing aqueous solutions can be made to pop open by heating them from the outside with infrared lasers. Patients could be administered nanocontainers carrying drugs to deliver it to a desired target where the drug then is released by laser light.
And finally, Die Welt this week deals with wrinkles and high tech attempts to avoid or get rid of them. Clinical studies in people with an average age of 87 prove that vitamin A1 (retinol) is useful to smooth skin. Also, light from LEDs is able to remove a water film caging the skin’s elastic fibers so that they become rigid. The method is best applied by pre-treating the skin with green tee polyphenols to deactivate free radicals generated by the LEDs. Moreover, scientists from Hamburg-based Skin Investigation and Technology SIT found out that eating one bar of dark chocolate a day also leads to a 34% improvement of skin elasticity after 6 months. Further attempts to eliminate wrinkles are being made by using signaling peptides activating collagen-producing cells and by polymers carrying nanoparticles that are injected between outer and inner skin layers. The resulting films disperse the compression forces within the skin, thereby “ironing” it from inside.
