Tag: unresectable tumors

Thermosome Reports Encouraging Clinical Data of THE001 in Advanced Soft Tissue Sarcomas

— Heat-triggered release mechanism unequivocally confirmed

— Favorable safety profile with good tolerability

— Signs of encouraging clinical activity in heavily pre-treated patients including meaningful progression-free survival (PFS)

— One participant with previously unresectable disease in DL2 underwent surgery, indicating no vital tumor cells in the target lesion

Munich, Germany – June 24, 2025 – Thermosome GmbH, a clinical-stage drug development company focused on targeted tumor therapies, today announced new, encouraging data from its ongoing Phase I clinical trial evaluating its lead compound THE001 (DPPG₂-TSL-DOX) in combination with regional hyperthermia (RHT) for the treatment of soft tissue sarcomas (STS). Read more…