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Company News: BioNTech to present interim PhaseI/II data for investigational mRNA vaccine in melanoma patients at AACR Annual Meeting 2017
– First Clinically Applicable, Systemic RNA-based Cancer Vaccine –
BioNTech AG, a fully-integrated biotechnology company pioneering individualized cancer immunotherapy, today announced that it will present interim data from an ongoing Phase I/II clinical trial of its Lipo-MERIT vaccine in patients with malignant melanoma at the 2017 Annual Meeting of the American Association for Cancer Research (AACR), taking place April 1 – 5 in Washington, DC.
This is the first example of a clinically applied systemic mRNA-based cancer immunotherapy.
Permanent Abstract Number: CT034
Poster: “A First-in-Human Phase I/II Clinical Trial Assessing Novel mRNA-lipoplex Nanoparticles for Potent Melanoma Immunotherapy”
Date: Monday, April 3, 2017
Session: PO.CT01 – Phase I Clinical Trials in Progress
Time: 8:00AM – 12:00PM Eastern Daylight Time
Location: Poster Section 33
The Phase I/II dose escalation Lipo-MERIT trial (NCT02410733) in melanoma patients assesses the safety and tolerability as well as the potency of inducing antigen-specific immune responses of the first systemic mRNA vaccine to be developed based on BioNTech’s mRNA nanoparticle immunotherapy platform.